Properdin Antibody (3A3E1)

Product Discontinued

Properdin Antibody (3A3E1) Summary

• Immunogen: Human properdin purified from human plasma.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CFP
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Functional
  • Immunoassay
  • Western Blot 1:100-1:1000

Reactivity Notes

Cross reacts with rabbit

Packaging, Storage & Formulations

• Storage: Store at 4°C.
• Buffer: PBS with 0.1% BSA
• Preservative: No Preservative
• Purity: Protein G purified

Alternate Names for Properdin Antibody (3A3E1)

• BFD
• CFP
• Complement Factor P
• complement factor properdin
• PFC
• PFCcomplement
• PFD
• Properdin

Background

Properdin in plasma is a mixture of cyclic dimers, trimers and tetramers. The molecular weight of the glycosylated monomer is 53 kDa. Properdin is a regulator protein of the alternative complement pathway. It stabilizes the C3 convertase excreting its effect by binding to C3b in the C3bBb complex and thereby inhibiting cleavage of C3b by factor I and increasing the affinity for factor B. Serum concentration is approximately 25 ug/mL.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CFP