PRL-3/PTP4A3 Antibody (334402) [Alexa Fluor™ Plus 680]

• Clone: 334402
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 680

PRL-3/PTP4A3 Antibody (334402) [Alexa Fluor™ Plus 680] Summary

• Specificity: Detects endogenous human, mouse and rat PRL-3 in Western blots. In Western blots, this antibody does not cross‑react with recombinant human PRL-1 or PRL‑2.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PRL-3/PTP4A3 Antibody (334402) [Alexa Fluor™ Plus 680]

• PRL3
• PRL-3
• PRL3EC 3.1.3.48
• PRL-3potentially prenylated protein tyrosine phosphatase
• PRL-Rprotein tyrosine phosphatase type IVA 3
• protein tyrosine phosphatase type IVA, member 3
• Protein-tyrosine phosphatase 4a3
• Protein-tyrosine phosphatase of regenerating liver 3
• PTP4A3

Background

Phosphatase of Regenerating Liver-3 (PRL-3), also known as PTP4A3, is an enzyme that removes phosphate modifications from tyrosine residues on proteins. Prenylation at the C-terminal end targets PRL-3 to membrane compartments in the cell, especially to early endosomes and the plasma membrane. Elevated levels of PRL-3 are observed in metastatic colorectal, ovarian, liver and skin cancers. PRL-3 levels may correlate with cell migration rates and tumor invasiveness.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.