PRELP Antibody (01) [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: ELISA
• Clone: 01
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

PRELP Antibody (01) [mFluor Violet 500 SE] Summary

• Immunogen: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PRELP (Accession#: NP_002716.1; Gln21-Ile382).
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: PRELP
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PRELP Antibody (01) [mFluor Violet 500 SE]

• 55 kDa leucine-rich repeat protein of articular cartilage
• MST161
• MSTP161
• PRELP
• prolargin proteoglycan
• Prolargin
• proline arginine-rich end leucine-rich repeat protein
• proline/arginine-rich end leucine-rich repeat protein
• Proline-arginine-rich end leucine-rich repeat protein
• SLRR2A
• SLRR2AMGC45323

Background

PRELP is encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRELP