Pregnancy Zone Protein Antibody (909813) [Unconjugated]

Images

 
Western blot shows lysate of human pregnancy sera. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human Pregnancy Zone Protein/PZP Monoclonal Antibody (Catalog # MAB8280) followed by HRP-conjugated Anti-Mouse IgG ...read more
Recombinant Human Pregnancy Zone Protein/PZP protein was serially diluted 2-fold and captured by Mouse Anti-Human Pregnancy Zone Protein/PZP Monoclonal Antibody (Catalog # MAB82801) coated on a Clear Polystyrene ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
909813
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Catalog# & Formulation Size Price

Pregnancy Zone Protein Antibody (909813) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Human embryonic kidney cell line HEK293-derived recombinant human Pregnancy Zone Protein/PZP
Thr26-Val1482
Accession # P20742
Specificity
Detects human Pregnancy Zone Protein/PZP in direct ELISAs.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
PZP
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 2 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Pregnancy Zone Protein Antibody (909813) [Unconjugated]

  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
  • CPAMD6
  • Pregnancy Zone Protein
  • pregnancy-zone protein
  • PZP

Background

Pregnancy Zone Protein (PZP), also known as C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6, is a 360 kDa secreted homodimeric glycoprotein, PZP monomer contains a region of decisive functional importance i.e. the bait region. This region serves as a substrate to a variety of proteinases, and cleavage in this domain causes a conformational change of the molecule. Human PZP is a member of the protease inhibitor I39 (alpha-2-macroglobulin) family of proteins.  Highest expression of human PZP is reported in liver, medium expression in ovary, heart and stomach. Also, this protein is found in plasma.  Over amino acids (aa) 26-1482, human PZP shares 56% aa sequence identity with mouse PZP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PZP
Uniprot