Host: Mouse Monoclonal
Host: Goat Polyclonal
Host: Rabbit Polyclonal
PZP is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
|Product By Gene ID
- pregnancy zone protein
- C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6
- pregnancy-zone protein
Bioinformatics Tool for Pregnancy Zone Protein
Discover related pathways, diseases and genes to Pregnancy Zone Protein. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.