PPP1R9B/Spinophilin Antibody [mFluor Violet 450 SE]

• Reactivity: Hu, Rt
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: mFluor Violet 450 SE

PPP1R9B/Spinophilin Antibody [mFluor Violet 450 SE] Summary

• Immunogen: E. coli-derived recombinant human PPP1R9B
  Lys289-Asp412
  Accession # Q96SB3
• Specificity: Detects human and rat PPP1R9B in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: PPP1R9B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PPP1R9B/Spinophilin Antibody [mFluor Violet 450 SE]

• FLJ30345
• neurabin II
• Neurabin-2
• neurabin-II
• PPP1R6
• PPP1R9
• PPP1R9B
• Protein phosphatase 1 regulatory subunit 9B
• protein phosphatase 1, regulatory (inhibitor) subunit 9B
• protein phosphatase 1, regulatory subunit 9B, spinophilin
• SPINO
• Spinophilin
• Spn

Background

Spinophilin, also known as Neurabin-2 and PPP1R9B, has 815 amino acids and is approximately 89kDa. Spinophilin is a scaffold protein that is involved in many signaling pathways, such as the cAMP pathway, the G-protein coupled receptor signaling pathway, the IL-6 pathway, and the Beta-Adrenergic signaling pathway. Spinophilin may be implicated in the linking of the plasma membrane to the actin cytoskeleton at synaptic junctions. Current research on Spinophilin is being performed in relation to several diseases and disorders including anorexia nervosa, Alzheimer's disease, schizophrenia, encephalitis, breast cancer, mood disorder, and glioblastoma. Spinophilin has also been shown to have interactions with CCKAR, CCKBR, ADRA1B, DRD2, and PPP1CA.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPP1R9B