PPAR gamma/NR1C3 [p Ser112] Antibody

Product Discontinued

PPAR gamma/NR1C3 [p Ser112] Antibody Summary

• Immunogen: Synthetic phosphopeptide derived from human PPARgamma around the phosphorylation site of Serine 112.
• Modification: p Ser112
• Specificity: p-PPARgamma (S112) pAb detects endogenous levels of PPARgamma protein only when phosphorylated at S112.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PPARG
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:1000
• Application Notes: Western blot (WB) analysis of p-PPARgamma (S112) pAb in extracts from Jurkat cells treated with Paclitaxel
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PPAR gamma/NR1C3 [p Ser112] Antibody

• CIMT1
• NR1C3
• NR1C3GLM1
• Nuclear receptor subfamily 1 group C member 3
• peroxisome proliferator-activated receptor gamma 1
• peroxisome proliferator-activated receptor gamma
• PPAR gamma
• PPARG
• PPARG1peroxisome proliferative activated receptor, gamma
• PPARG2PPARgamma
• PPAR-gamma

Background

Peroxisome proliferators are non genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY14,643, as well as by some fatty acids. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PPAR gamma/NR1C3 Antibody (NBP1-51406)(1)

Publication using NBP1-51406

• Chen YR, Chang KT, Tsai MJ et al. Antrodia cinnamomea profoundly exalted the reversion of activated hepatic stellate cells by the alteration of cellular proteins. Food Chem. Toxicol. 2014-04-18 [PMID: 24751970] (WB, Rat)

FAQs for PPAR gamma/NR1C3 Antibody (NBP1-51406). (Showing 1 - 1 of 1 FAQ).

1. Would you please help confirm if there is any reference available for NBP1-51406?
   • Unfortunately we do not have any references available for this anitbody.

Bioinformatics

• Gene Symbol: PPARG