Polypeptide GalNac Transferase 3/GALNT3 Antibody - Azide and BSA Free

Western Blot: Polypeptide GalNac Transferase 3/GALNT3 Antibody [H00002591-D01P] - Analysis of GALNT3 expression in transfected 293T cell line by GALNT3 polyclonal antibody.Lane 1: GALNT3 transfected lysate(15.90 KDa).Lane 2: Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Polypeptide GalNac Transferase 3/GALNT3 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: GALNT3 (AAH56246.1, 1 a.a. - 141 a.a.) full-length human protein. MERNMKNKNKMLDLMLEAVNNIKDAMPKMQIGAPVRQNIDAGERPCLQGYYTAAELKPVLDRPPQDSNAPGASGKAFKTTNLSVEEQKEKERGEAKHCFNAFASDRISLHRDLGPDTRPPEYVEEYLLFILYHQALQGREG
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GALNT3
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: It has been used for WB and Functional.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Polypeptide GalNac Transferase 3/GALNT3 Antibody - Azide and BSA Free

• EC 2.4.1.41
• GalNAc transferase 3
• GalNAc-T3
• GalNAc-T3DKFZp686C10199
• GALNT3
• HFTC
• HFTCMGC61909
• HHS
• HHSPolypeptide GalNAc transferase 3
• polypeptide GalNAc-transferase T3
• polypeptide N-acetylgalactosaminyltransferase 3
• pp-GaNTase 3
• Protein-UDP acetylgalactosaminyltransferase 3
• UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3
• UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 3 (GalNAc-T3)

Background

GALNT3, also known as Polypeptide N-acetylgalactosaminyltransferase 3, has a 633 amino acid long isoform that is 73 kDa and a short 192 amino acid isoform that is 22 kDa; is located in the Golgi apparatus; plays a central role in phosphate homeostasis; acts as a catalyzer in the initiation of O-linked oligosaccharide biosynthesis, and the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor; shows an activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5; and glycosylates FGF23, and probably fibronectin in vivo too. Studies on this protein have shown a relationship with the following diseases and disorders: tumoral calcinosis, hyperphosphatemic calcinosis, hyperostosis-hyperphosphatemia syndrome, hyperphosphatemic familial tunoral calcinisis, normophosphatemic familial tumoral calcinosis, testicular microlithiasis, bile duct carcinoma, periostitis, squamous cell carcinoma, diabetes mellitus, colon adenocarcinoma, lung adenocarcinoma, pancreatic cancer, metabolic disorders, and lung cancer. This protein has also been shown to have interactions with CIGALT1, CIGALT1C1, ST6GALNAC1, B3GNT6, and GCNT1 in pathways such as O-linked glycosylation of mucins, metabolism of proteins, and post-translational protein modification.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALNT3
• Uniprot:
  • AAH56246.1(Human)