Podocalyxin Like Antibody [HRP]

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-41510H
    • Availability
      Product Discontinued

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Podocalyxin Like Antibody [HRP] Summary

Immunogen
A synthetic peptide within an internal region (residues 350-450) of the human Podocalyxin protein. [Swiss-Prot# O00592]
Localization
Membrane
Marker
Podocytes /Apical Marker, Endothelial Cell Marker
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PODXL
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This Podocalyxin antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot analysis. In WB a band is observed at ~52 kDa. There may be a non-specific band observed at ~27 kDa depending on the lysates used. In ICC/IF membrane staining was observed.
Readout System

Reactivity Notes

Human and mouse. Immunogen sequence has 80% homology to canine and 76% homology to rat.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Podocalyxin Like Antibody [HRP]

  • GCTM
  • Gp200MGC138240
  • PCLP
  • PCLP1
  • PCLP-1
  • PCLPGCTM-2 antigen
  • PCpodocalyxin
  • POD XL
  • Podocalyxin
  • Podocalyxin-like protein 1
  • podocalyxin-like
  • PODXL

Background

Podocalyxin is a CD34 family member expressed by podocytes, vascular endothelium, mesothelium, and a subset of hematopoietic progenitors. It is the major sialoprotein in the glycocalyx of glomerular podocytes. The physiologic role of podocalyxin in leukemic blasts is unknown. However, it is thought of as a candidate prostate cancer tumor aggressiveness gene. Podocalyxin appears to complement CD34 as a useful cell surface marker for hemangioblasts, the common precursors of hematopoietic and endothelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol PODXL
Entrez