Plxdc2 Antibody - BSA Free

Western Blot: Plxdc2 Antibody [NBP1-76859] - Human colon tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 ug/ml.

Immunohistochemistry-Paraffin: Plxdc2 Antibody [NBP1-76859] - Human brain tissue using Plxdc2 antibody at 2.5 ug/ml.

Immunocytochemistry/ Immunofluorescence: Plxdc2 Antibody - BSA Free [NBP1-76859] - Immunofluorescence of Plxdc2 in Human Brain cells with Plxdc2 antibody at 50 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Plxdc2 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human Plxdc2. The immunogen is located within the last 50 amino acids of Plxdc2. Amino Acid Squence: RRPSRWPAMKFRRGSGH
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLXDC2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 0.5-1 ug/ml
• Control Peptide:

  Plxdc2 Peptide (NBP1-76859PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Plxdc2 Antibody - BSA Free

• plexin domain containing 2,1200007L24Rik
• plexin domain-containing protein 2
• TEM7RFLJ14623
• Tumor endothelial marker 7-related protein

Background

Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLXDC2
• Uniprot:
  • Q6UX71(Human)