Plexin C1 Antibody

Immunocytochemistry/Immunofluorescence: Plexin C1 Antibody [NBP2-57282] - Staining of human cell line SK-MEL-30 shows localization to mitochondria.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Plexin C1 Antibody Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SKELSRKQSQQLELLESELRKEIRDGFAELQMDKLDVVDSFGTVPFLDYKHFALRTFFPESGGFTHIFTEDMHNRDANDKNESLTALDALICNKSFLVTVIHTL
• Predicted Species: Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLXNC1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
• Application Notes: Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  Plexin C1 Recombinant Protein Antigen (NBP2-57282PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Plexin C1 Antibody

• CD232 antigen
• CD232
• plexin (semaphorin receptor)
• Plexin C1
• PLXNC1
• PLXN-C1
• receptor for viral semaphorin protein
• receptor for virally-encoded semaphorin
• VESPR
• VESPRplexin-C1
• Virus-encoded semaphorin protein receptor

Background

Plexin C1, also known by its gene name PLXNC1, is approximately 176kDa and 1,568 amino acids in length. Plexin C1 is localized to the cellular membrane as a transmembrane receptor for the Semaphorins family of proteins. Plexin C1 may be implicated in the regulation of melanocyte adhesion and may be a melanoma tumor suppressor. Current research on Plexin C1 is being performed in relation to several diseases and disorders including Parkinson's disease, leukemia, kidney disease, melanoma, smallpox, prostate cancer, malignant glioma, renal cell carcinoma, ovarian cancer, pancreatic cancer, hepatitis, prostatitis, and pancreatitis. Plexin C1 has also been shown to have interactions with SEMA7A in the axon guidance pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLXNC1