Plexin C1 Antibody (2H11C11) - BSA Free

ELISA: Plexin C1 Antibody (2H11C11) [NBP3-27143] - Black line: Control Antigen (100 ng); Purple line: Antigen (10 ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)

Flow Cytometry: Plexin C1 Antibody (2H11C11) [NBP3-27143] - Analysis of HL-60 cells using Plexin C1 mouse mAb (green) and negative control (red).

Western Blot: Plexin C1 Antibody (2H11C11) [NBP3-27143] - Analysis using Plexin C1 mAb against human Plexin C1 (AA: extra 35-234) recombinant protein. (Expected MW is 47.2 kDa)

Western Blot: Plexin C1 Antibody (2H11C11) [NBP3-27143] - Analysis using Plexin C1 mAb against HEK293 (1) and Plexin C1 (AA: extra 35-234)-hIgGFc transfected HEK293 (2) cell lysate.

• Reactivity: Hu
• Applications: WB, ELISA, Flow
• Clone: 2H11C11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Plexin C1 Antibody (2H11C11) - BSA Free Summary

• Immunogen: Purified recombinant fragment of human Plexin C1 (AA: extra 35-234) expressed in E. Coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PLXNC1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Flow Cytometry 1:200 - 1:400
  • Western Blot 1:500 - 1:2000
• Theoretical MW: 175.7 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for Plexin C1 Antibody (2H11C11) - BSA Free

• CD232 antigen
• CD232
• plexin (semaphorin receptor)
• Plexin C1
• PLXNC1
• PLXN-C1
• receptor for viral semaphorin protein
• receptor for virally-encoded semaphorin
• VESPR
• VESPRplexin-C1
• Virus-encoded semaphorin protein receptor

Background

Plexin C1, also known by its gene name PLXNC1, is approximately 176kDa and 1,568 amino acids in length. Plexin C1 is localized to the cellular membrane as a transmembrane receptor for the Semaphorins family of proteins. Plexin C1 may be implicated in the regulation of melanocyte adhesion and may be a melanoma tumor suppressor. Current research on Plexin C1 is being performed in relation to several diseases and disorders including Parkinson's disease, leukemia, kidney disease, melanoma, smallpox, prostate cancer, malignant glioma, renal cell carcinoma, ovarian cancer, pancreatic cancer, hepatitis, prostatitis, and pancreatitis. Plexin C1 has also been shown to have interactions with SEMA7A in the axon guidance pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLXNC1