PIN/DLC8 Antibody (98618)

• Reactivity: Hu
• Applications: WB, IP
• Clone: 98618
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

PIN/DLC8 Antibody (98618) Summary

• Immunogen: E. coli-derived recombinant human PIN
  Trp2-Gly89
  Accession # P63167
• Specificity: Detects human PIN in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: DYNLL1
• Purity Statement: Protein A or G purified from ascites

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2.5-5 ug/10^6 cells
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PIN/DLC8 Antibody (98618)

• cytoplasmic dynein light polypeptide
• DLC1
• DLC1DNCLC1
• DLC8
• DLC8MGC126137
• DNCL1
• DNCL1MGC126138
• DNCLC1
• dynein light chain 1, cytoplasmic
• Dynein light chain LC8-type 1
• dynein, cytoplasmic, light polypeptide 1
• dynein, light chain, LC8-type 1,8 kDa dynein light chain
• DYNLL1
• hdlc1
• LC8
• LC8a
• PIN
• PINLC8a
• Protein inhibitor of neuronal nitric oxide synthase

Background

PIN (protein inhibitor of neuronal nitric oxide synthase), also called DLC8, is an 8 kDa cytoplasmic protein that is a light chain of the dynein molecular motor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PIN/DLC8 Antibody (MAB877)(1)

Publication using MAB877

• Bergen JM, Pun SH Evaluation of an LC8-binding peptide for the attachment of artificial cargo to dynein. Mol. Pharm., 2007-01-01;4(1):119-28. 2007-01-01 [PMID: 17274669] (ELISA Development, Human)

Bioinformatics

• Gene Symbol: DYNLL1
• Uniprot:
  • P63167()