PIK3R4 Antibody (576514) [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: WB
• Clone: 576514
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

PIK3R4 Antibody (576514) [Janelia Fluor® 646] Summary

• Immunogen: E. coli-derived recombinant human PIK3R4
  Gln58-Arg230
  Accession # Q99570
• Specificity: Detects human PIK3R4 in Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: PIK3R4
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PIK3R4 Antibody (576514) [Janelia Fluor® 646]

• EC 2.7.11.1
• MGC102700
• p150
• phosphatidylinositol 3-kinase-associated p150
• Phosphoinositide 3-kinase adaptor protein
• phosphoinositide 3-kinase regulatory subunit 4
• phosphoinositide-3-kinase, regulatory subunit 4
• phosphoinositide-3-kinase, regulatory subunit 4, p150
• PI3-kinase p150 subunit
• PI3-kinase regulatory subunit 4
• PIK3R4
• VPS 15
• VPS15

Background

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIK3R4