Phospholipid Scramblase 1/PLSCR1 Antibody

Images

 
Western Blot: Phospholipid Scramblase 1/PLSCR1 Antibody [NBP1-32588] - Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Phospholipid scramblase 1 antibody [N1C3] ...read more
Immunocytochemistry/ Immunofluorescence: Phospholipid Scramblase 1/PLSCR1 Antibody [NBP1-32588] - A431 cells were fixed in ice-cold MeOH for 5 min. Green: PLSCR1 protein stained by Scramblase1 antibody [N1C3] diluted at ...read more
Immunohistochemistry-Paraffin: Phospholipid Scramblase 1/PLSCR1 Antibody [NBP1-32588] - MDAMB468 xenograft , using phospholipid scramblase 1 antibody at 1:500 dilution.Antigen Retrieval: Trilogy™ (EDTA based, pH ...read more
Western Blot: Phospholipid Scramblase 1/PLSCR1 Antibody [NBP1-32588] - Phospholipid scramblase is required for phosphatidylserine and Akt relocalization.CaSki cells were mock-infected or infected with HSV-2(G) and 15 ...read more
Expression of hypoxia-inducible alpha subunits in normal and diseased lung tissue. HIF-1 alpha and HIF-2 alpha expression are more evident in fibroblasts from idiopathic pulmonary fibrosis (a, d) than from lung tissue ...read more

Product Details

Summary
Reactivity Hu, RMSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Phospholipid Scramblase 1/PLSCR1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Phospholipid scramblase 1. The exact sequence is proprietary.
Localization
Membrane, Single-pass type II membrane protein
Predicted Species
Rhesus Macaque (96%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PLSCR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
Theoretical MW
35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-32588 in the following applications:

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS pH7, 1% BSA, 20% Glycerol
Preservative
0.01% Thimerosal
Purity
Immunogen affinity purified

Alternate Names for Phospholipid Scramblase 1/PLSCR1 Antibody

  • Erythrocyte phospholipid scramblase
  • MMTRA1B
  • MMTRA1BCa(2+)-dependent phospholipid scramblase 1
  • Phospholipid Scramblase 1
  • PL scramblase 1
  • PLSCR1

Background

Phospholipid scramblase 1 (PLSCR1) is a member of the PLSCR protein family. These proteins are ATP-independent lipid translocators localized to the plasma membrane and is involved in a calcium dependent, nonspecific and rapid redistribution (scrambling) of phospholipids when a perturbation of plasma membrane asymmetry is needed for the cell (e.g. following cell activation, injury, or apoptosis). The expression of PLSCR1 is found in a variety of tissue and can be stress-induced. Upon stimulation (e.g. interferon stimulation), a portion of newly synthesized PLSCR1 is imported into the nucleus (instead of inserted into the plasma membrane) and interacts with DNA, consistent with a role in gene regulation. PLSCR1 may be closely associated with the pathophysiology underlying infection and inflammation, which manifest marked changes in energy consumption and lipid metabolism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for Phospholipid Scramblase 1/PLSCR1 Antibody (NBP1-32588)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Biacore Binding Assay.


Filter By Application
Biacore Binding Assay
(1)
All Applications
Filter By Species
Human
(2)
All Species

Reviews for Phospholipid Scramblase 1/PLSCR1 Antibody (NBP1-32588) (0)

There are no reviews for Phospholipid Scramblase 1/PLSCR1 Antibody (NBP1-32588). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Phospholipid Scramblase 1/PLSCR1 Antibody (NBP1-32588) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Phospholipid Scramblase 1/PLSCR1 Products

Research Areas for Phospholipid Scramblase 1/PLSCR1 Antibody (NBP1-32588)

Find related products by research area.

Blogs on Phospholipid Scramblase 1/PLSCR1

There are no specific blogs for Phospholipid Scramblase 1/PLSCR1, but you can read our latest blog posts.
mFluor Violet Conjugated Antibodies

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Phospholipid Scramblase 1/PLSCR1 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol PLSCR1