Recombinant Human PGD2 Synthase/PTGDS Protein

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SDS-Page: Recombinant Human PGD2 Synthase/PTGDS Protein [NBP1-51078] - 15% SDS-PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human PGD2 Synthase/PTGDS Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 23-190 of Human PGD2 Synthase/PTGDS

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAPEAQVSVQ PNFQQDKFLG RWFSAGLASN SSWLREKKAA LSMCKSVVAP ATDGGLNLTS TFLRKNQCET RTMLLQPAGS LGSYSYRSPH WGSTYSVSVV ETDYDQYALL YSQGSKGPGE DFRMATLYSR TQTPRAELKE KFTAFCKAQG FTEDTIVFLP QTDKCMTEQ

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
PTGDS
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
20.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 1mM EDTA, 0.1M NaCl
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human PGD2 Synthase/PTGDS Protein

  • Beta-trace protein
  • Cerebrin-28
  • EC 5.3.99.2
  • Glutathione-independent PGD synthase
  • glutathione-independent PGD synthetase
  • lipocalin-type prostaglandin D synthase
  • Lipocalin-type prostaglandin-D synthase
  • L-PGDS
  • PDS
  • PGD2 Synthase
  • PGD2
  • PGDS2
  • PGDSLPGDS
  • PH2DISO
  • prostaglandin D synthase
  • prostaglandin D2 synthase (21kD, brain)
  • prostaglandin D2 synthase 21kDa (brain)
  • Prostaglandin-D2 synthase
  • prostaglandin-H2 D-isomerase
  • PTGDS

Background

Prostaglandin-H2 D-isomerase, also known as PTGDS, is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a beta-amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimer's disease. Recombinant human PTGDS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol PTGDS
Entrez