PGD2 Synthase/PTGDS Products

Antibodies
PGD2 Synthase/PTGDS Antibody
PGD2 Synthase/PTGDS Antibody
NB110-59909
Species: Hu, Mu, Rt, Po, Bv, Eq, Fe, Pm, Rb
Applications: WB, Simple Western
Host: Rabbit Polyclonal
PGD2 Synthase/PTGDS Antibody
PGD2 Synthase/PTGDS Antibody
NB110-59911
Species: Hu, Mu, Rt, Bv, Ca, Fe, Pm, Rb
Applications: WB
Host: Rabbit Polyclonal
PGD2 Synthase/PTGDS Antibody
PGD2 Synthase/PTGDS Antibody
NBP1-79280
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
PGD2 Synthase/PTGDS Overexpre ...
PGD2 Synthase/PTGDS Overexpression...
H00005730-T01
Species: Hu
Applications: WB
PGD2 Synthase/PTGDS Overexpre ...
PGD2 Synthase/PTGDS Overexpression...
NBL1-14930
Applications: WB
Proteins
PGD2 Synthase/PTGDS Peptide
PGD2 Synthase/PTGDS Peptide
NB110-59909PEP
Species: Hu
PGD2 Synthase/PTGDS Peptide
PGD2 Synthase/PTGDS Peptide
NB110-59911PEP
Species: Hu
PGD2 Synthase/PTGDS Recombina ...
PGD2 Synthase/PTGDS Recombinant Pr...
NBP1-81291PEP
Species: Hu
Applications: AC
RNAi
PGD2 Synthase/PTGDS RNAi
PGD2 Synthase/PTGDS RNAi
H00005730-R01
Species: Hu

Description

Prostaglandin D Synthase (PTGDS), is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS has also been implicated in the development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement (NREM) sleep. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a Beta-Amyloid chaperone and may have a role in the deposition of amyloid-b plaques in Alzheimer's disease.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 5730
Alternate Names
  • Cerebrin-28
  • EC 5.3.99.2
  • prostaglandin-H2 D-isomerase
  • PGD2 synthase
  • prostaglandin D synthase
  • PGDS2
  • lipocalin-type prostaglandin D synthase
  • PDS
  • glutathione-independent PGD synthetase
  • Prostaglandin-D2 synthase
  • cerebrin-28
  • Lipocalin-type prostaglandin-D synthase
  • PGD2
  • Glutathione-independent PGD synthase
  • Beta-trace protein
  • L-PGDS
  • PGDSLPGDS
  • prostaglandin D2 synthase (21kD, brain)
  • prostaglandin D2 synthase 21kDa (brain)

Research Areas for PGD2 Synthase/PTGDS

Find related products by research area and learn more about each of the different research areas below.

Mast Cell Markers
Neuroscience
Signal Transduction

Bioinformatics Tool for PGD2 Synthase/PTGDS

Discover related pathways, diseases and genes to PGD2 Synthase/PTGDS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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