PFKP Antibody (OTI1D6) [Allophycocyanin/Cy7]

• Reactivity: Hu, Mu, Rt
• Applications: Flow, ICC/IF, IHC, KO
• Clone: OTI1D6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin/Cy7

PFKP Antibody (OTI1D6) [Allophycocyanin/Cy7] Summary

• Immunogen: Full length recombinant protein of human PFKP (NP_002618) produced in HEK293T cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PFKP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockout Validated
• Application Notes: Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PFKP Antibody (OTI1D6) [Allophycocyanin/Cy7]

• 6-phosphofructokinase type C
• 6-phosphofructokinase, platelet type
• EC 2.7.1
• EC 2.7.1.11
• PFK-CFLJ40226
• PFKFplatelet type
• Phosphofructokinase 1
• phosphofructokinase, platelet
• phosphohexokinase

Background

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PFKP