Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, KO
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.[supplied by OMIM]
Bioinformatics
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
5214 |
Alternate Names |
- 6-phosphofructokinase type C
- 6-phosphofructokinase, platelet type
- EC 2.7.1
- EC 2.7.1.11
- PFK-CFLJ40226
- PFKFplatelet type
- Phosphofructokinase 1
- phosphofructokinase, platelet
- Phosphohexokinase
- phosphohexokinase
|
Research Areas for PFKP
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism