Persephin Antibody [PE]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: PE

Persephin Antibody [PE] Summary

• Immunogen: E. coli-derived recombinant mouse Persephin
  Ala61-Gly156
  Accession # O70300.1
• Specificity: Detects mouse Persephin in direct ELISAs and Western blots. In Western blots, approximately 10% cross‑reactivity with recombinant human Persephin is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: PSPN
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for Persephin Antibody [PE]

• Persephin
• PSP
• PSPN

Background

The protein encoded by the Persephin gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PSPN