PDE6G Antibody

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

PDE6G Antibody Summary

• Immunogen: Synthetic cyclic peptide common to all PDE6 gamma variants.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDE6G
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PDE6G Antibody

• DKFZp686C0587
• GMP-PDE gamma
• MGC125749
• PDE6G
• PDEG
• phosphodiesterase 6G, cGMP-specific, rod, gamma
• retinal rod rhodopsin-sensitive cGMP 3'-5'-cyclic phosphodiesterase subunit gamma
• rod cG-PDE G
• RP57

Background

PDE6G encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. PDE6G is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. PDE6G is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PDE6G