PDE6G Antibody (OTI2F5) [mFluor Violet 610 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI2F5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

PDE6G Antibody (OTI2F5) [mFluor Violet 610 SE] Summary

• Immunogen: Full length human recombinant protein of human PDE6G(NP_002593) produced in HEK293T cell.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PDE6G
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PDE6G Antibody (OTI2F5) [mFluor Violet 610 SE]

• DKFZp686C0587
• GMP-PDE gamma
• MGC125749
• PDE6G
• PDEG
• phosphodiesterase 6G, cGMP-specific, rod, gamma
• retinal rod rhodopsin-sensitive cGMP 3'-5'-cyclic phosphodiesterase subunit gamma
• rod cG-PDE G
• RP57

Background

PDE6G encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. PDE6G is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. PDE6G is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PDE6G