PCYT1B Antibody [DyLight 550]

Product Discontinued

PCYT1B Antibody [DyLight 550] Summary

• Immunogen: phosphate cytidylyltransferase 1, choline, beta. (Uniprot# Q9Y5K3)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PCYT1B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PCYT1B Antibody [DyLight 550]

• CCT B
• CCTB
• CCT-betaEC 2.7.7.15
• choline-phosphate cytidylyltransferase B
• CT B
• CTB
• CTP:phosphocholine cytidylyltransferase B
• EC 2.7.7
• phosphate cytidylyltransferase 1, choline, beta isoform
• phosphate cytidylyltransferase 1, choline, beta
• Phosphorylcholine transferase B

Background

TCP1 beta is a subunit of a cytosolic hetero-oligomer chaperon that is known to be involved in the folding of actin and tubulin. This protein is a member of the chaperonin family, which includes Escherichia coli GroEL, the mitochondrial heat-shock protein Hsp60, the plastid Rubisco-subunit-binding protein and the archaebacterial protein TF55. These chaperonins assist the folding of proteins upon ATP hydrolysis. Nine different subunits of TCP-1 containing chaperonin complexes from mammalian testis and seven different subunits of mouse F9 cells have been identified. It has been suggested that each CCT subunit has a specific, independent function, as they are highly diverged from each other but conserved from mammals to yeast. The expansion in the number of types of CCT subunit, compared with other chaperonins, has allowed CCT to carry out more complex functions that are required for the folding and assembly of highly evolved eukaryotic proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCYT1B