PARK2 (AAH22014, 288 a.a. - 387 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PCVGTGDTVVLRGALGGFRRGVAGCPNSLIKELHHFRILGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGYGQRRTK
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.4)
Quality control test: Antibody Reactive Against Recombinant Protein.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Parkin Antibody (1H4)
E3 ubiquitin ligase
E3 ubiquitin-protein ligase parkin
Parkinson disease protein 2
Parkinson juvenile disease protein 2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
PDJjuvenile) 2, parkin
The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Western Blot: Parkin Antibody (1H4) [H00005071-M01] - Western blot analysisi was performed in mouse skeletal muscle proteins, separated by 4-12% SDS-PAGE. Proteins were transferred on nitrocellulose membrane and blocked in 5% non-fat milk for 1h at room temperature. Anti Parkin antibody was used 1:1000
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