PARD6A Antibody

Product Discontinued

PARD6A Antibody Summary

• Immunogen: Synthetic peptide derived from internal domains of PAR-6A protein
• Specificity: Reacts with 38 kDa protein.
  Cross reacts with proteins from mouse, rat and other species.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PARD6A
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50- 1:200
  • Western Blot 1:100- 1:1000
• Theoretical MW: 38 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse, Rat

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris , 0.1M Glycine and 2% Sucrose
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Lyophilized powder, reconstituted in distilled water.

Alternate Names for PARD6A Antibody

• PAR-6 alpha
• par-6 partitioning defective 6 homolog alpha (C. elegans)
• PAR-6
• PAR6A
• PAR6alpha
• PAR-6Apar-6 (partitioning defective 6, C.elegans) homolog alpha
• PAR6C
• partitioning defective 6 homolog alpha
• partitioning defective-6 homolog alpha
• partitioning-defective protein 6
• Tax interaction protein 40
• TAX40
• Tax-interacting protein 40
• TIP-40PAR6

Background

his gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PARD6A
• Uniprot:
  • Q9NPB6(Human)