PARD3/Par3 Antibody (833517) [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 833517
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

PARD3/Par3 Antibody (833517) [mFluor Violet 610 SE] Summary

• Immunogen: E. coli-derived recombinant human PARD3/Par3
  Tyr451-Glu555
  Accession # Q8TEW0
• Specificity: Detects human PARD3/Par3 in ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human PARD3b/Par3b is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PARD3
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PARD3/Par3 Antibody (833517) [mFluor Violet 610 SE]

• ASIP
• Baz
• Bazooka
• FLJ21015
• par-3 partitioning defective 3 homolog (C. elegans)
• PAR3
• PAR3A
• PAR3C.elegans) homolog
• PARD3
• SE2-5L16
• SE2-5LT1
• SE2-5T2

Background

PARD3 is an adaptor protein involved in asymmetrical cell division and cell polarization processes. PARD3 seems to play a central role in the formation of epithelial tight junctions. PARD3 may affect the quality of hair pigmentation, and act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone (2-3). PARD3 may also play a role in neuroendocrine aspects of melanocortin action, and have a functional role in regulating lipid metabolism in adipocytes (4-5). Recent studies have suggested PARD3 (Par-3) is essential in the formation of myelin sheaths on neuronal axons.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PARD3