PARC Antibody


Western Blot: PARC Antibody [NB100-2300] - Detection of Human PARC/H7-AP1 on HeLa whole cell lysate using NB100-2300. Normal rabbit IgG was used as a control for immunoprecipitation (IP Control).

Product Details

Reactivity HuSpecies Glossary
Applications WB, IP
1.0 mg/ml

Order Details

PARC Antibody Summary

The immunogen recognized by this antibody maps to a region between residues 900 and 950 of human P53-associated parkin-like cytoplasmic protein using the numbering given in TrEMBL entry Q8IWT3 (GeneID 23113).
Predicted Species
Primate (100%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-citrate/phosphate buffer, pH 7 to 8
0.09% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Reactivity Notes

Human. Based on 100% sequence identity, this antibody is predicted to react with Gorilla.

Alternate Names for PARC Antibody

  • CUL-9
  • cullin 9
  • cullin-9
  • DKFZp686G1042
  • H7AP1DKFZp686P2024
  • p53-associated parkin-like cytoplasmic protein
  • PARCKIAA0708
  • parkin-like cytoplasmic p53 binding protein
  • RP3-330M21.2
  • UbcH7-associated protein 1


PARC is a cytoplasmic anchor protein in p53 associated protein complexes. PARC directly interacted and formed an approximately 1MD complex with p53 in the cytoplasm of unstressed cells. In the absence of stress, inactivation of PARC induced nuclear localization of endogenous p53 and activated p53 dependent apoptosis. Overexpression of PARC promoted cytoplasmic sequestration of ectopic p53. Furthermore, abnormal cytoplasmic localization of p53 was observed in a number of neuroblastoma cell lines; RNA interference-mediated reduction of endogenous PARC significantly sensitized these neuroblastoma cells in the DNA damage response. These results revealed that PARC is a critical regulator in controlling p53 subcellular localization and subsequent function.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


Isotype Controls

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Bioinformatics Tool for PARC Antibody (NB100-2300)

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Diseases for PARC Antibody (NB100-2300)

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Contact Information

Product PDFs


Gene Symbol CUL9

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