PAG3 Recombinant Protein



Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA, PA
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

PAG3 Recombinant Protein Summary

PAG3 (Human) GST-Tagged Recombinant Protein

Source: Wheat Germ (in vitro)

in vitro wheat germ expression system
Details of Functionality
This protein is not active and should not be used for experiments requiring activity.

Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Please see the vial label for concentration. If unlisted please contact technical services.


Application Notes
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.


This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PAG3 Recombinant Protein

  • arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
  • centaurin, beta 3
  • CENTB3
  • DDEF2FLJ42910
  • development and differentiation enhancing factor 2
  • Development and differentiation-enhancing factor 2
  • KIAA0400AMAP2
  • Pap-alpha
  • Paxillin-associated protein with ARF GAP activity 3
  • PYK2 C terminus-associated protein
  • Pyk2 C-terminus-associated protein
  • SHAG1


This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Video Protocols

WB Video Protocol

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Contact Information

Product PDFs


Gene Symbol ASAP2

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