Human Osteopontin/OPN Recombinant Protein

Images

 
There are currently no images for Osteopontin/OPN Recombinant Protein (NBP2-36588).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Func, PAGE, Bioactivity
Concentration
LYOPH

Order Details

Human Osteopontin/OPN Recombinant Protein Summary

Description
A biologically active protein corresponding to SPP1.
Preparation
Method
Lyophilized from 0.2 mm filtered concentrated solution in PBS.
Details of Functionality
When immobilized, rhOsteopontin supports more than 30% human HEK-293 cell adhesion.
Source
Mouse myeloma cell line
Protein/Peptide Type
Recombinant Protein
Gene
SPP1
Endotoxin Note
Less than 1 EU/mg of the rHuOsteopontin as determined by LAL method.

Applications/Dilutions

Dilutions
  • Bioactivity
  • Functional
  • SDS-Page

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Concentration
LYOPH
Reconstitution Instructions
Centrifuge prior to opening. Reconstitute with PBS to a final concentration of 0.1 mg/ml. Further dilutions should be made in appropriately buffered solutions.

Notes

This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.

Alternate Names for Human Osteopontin/OPN Recombinant Protein

  • BNSP
  • Bone sialoprotein 1
  • Eta-1
  • MGC110940
  • Nephropontin
  • OPN
  • Osteopontin
  • secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1)
  • secreted phosphoprotein-1 (osteopontin, bone sialoprotein)
  • Spp1
  • SPP-1
  • SPP1/CALPHA1 fusion
  • Urinary stone protein
  • uropontin

Background

Osteopontin (OPN), also known as SPP1, Eta-1, or BSP, is a highly acidic, 45-75 kDa secreted molecule in the SIBLING family of matricellular proteins. It can be variably modified with O- and N-glycosylation, sulfation, phosphorylation, and transglutamination. OPN binds several integrins and can bind additional integrins after it is proteolytically cleaved. OPN is prominently expressed in mineralized tissues. It inhibits bone mineralization and kidney stone formation and promotes inflammation, cell adhesion, and cell migration. OPN expression is upregulated during inflammation, obesity, atherosclerosis, cancer, and tissue damage, and it contributes to the pathophysiology of these conditions.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB1419
Species: Hu, Rt
Applications: CyTOF-ready, ICC, IHC, ICFlow
AF4014
Species: Hu
Applications: WB
AF942
Species: Mu
Applications: CyTOF-ready, ICC, IHC, ICFlow, WB
DPI00
Species: Hu
Applications: ELISA
NB110-3638
Species: Hu, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, RI, WB
DCC270
Species: Hu
Applications: ELISA
NBP2-32263
Species: Hu, Mu
Applications: IHC, IP, WB
NBP1-89131
Species: Hu
Applications: ICC/IF, IHC, IHC-P
NBP1-89133
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
NBP1-89134
Species: Hu
Applications: IHC, IHC-P
DY805
Species: Hu
Applications: ELISA
355-BM/CF
Species: Hu, Mu, Rt
Applications: BA
NBP1-47386
Species: Hu, Mu, Rb(-)
Applications: ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-P, WB
NBP1-91258
Species: Bv, Ca, Eq, Fe, Hu, Mu, Po, Rt
Applications: ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
DVE00
Species: Hu
Applications: ELISA
NBP2-92546
Species: Hu, Mu, Rt
Applications: ICC/IF, WB
D6050
Species: Hu
Applications: ELISA
NBP2-36588
Species: Hu
Applications: Func, PAGE, Bioactivity

Publications for Osteopontin/OPN Recombinant Protein (NBP2-36588) (0)

There are no publications for Osteopontin/OPN Recombinant Protein (NBP2-36588).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Osteopontin/OPN Recombinant Protein (NBP2-36588) (0)

There are no reviews for Osteopontin/OPN Recombinant Protein (NBP2-36588). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

FAQs for Osteopontin/OPN Recombinant Protein (NBP2-36588) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Other Available Formats

Additional Osteopontin/OPN Products

Bioinformatics Tool for Osteopontin/OPN Recombinant Protein (NBP2-36588)

Discover related pathways, diseases and genes to Osteopontin/OPN Recombinant Protein (NBP2-36588). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Osteopontin/OPN Recombinant Protein (NBP2-36588)

Discover more about diseases related to Osteopontin/OPN Recombinant Protein (NBP2-36588).
 

Pathways for Osteopontin/OPN Recombinant Protein (NBP2-36588)

View related products by pathway.

PTMs for Osteopontin/OPN Recombinant Protein (NBP2-36588)

Learn more about PTMs related to Osteopontin/OPN Recombinant Protein (NBP2-36588).

Blogs on Osteopontin/OPN.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents
Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...  Read full blog post.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Human Osteopontin/OPN Recombinant Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol SPP1