Osteopontin/OPN Products

Description

Osteopontin is the principal phosphorylated glycoprotein of bone and is expressed in a limited number of other tissues including dentine. Osteopontin is produced by osteoblasts under stimulation by calcitriol and binds tightly to hydroxyapatite. It is also involved in the anchoring of osteoclasts to the mineral of bone matrix via the vitronectin receptor, which has specificity for osteopontin. Osteopontin is overexpressed in a variety of cancers, including lung, breast, colorectal, stomach, ovarian, melanoma and mesothelioma.

Bioinformatics

Uniprot	AAH07016 Human AAH07016.1 Human AAH17387.1 Human B2RDA1 Human NM_000582 Human NP_000573 Human NP_000573.1 Human NP_001035147 Human NP_001035149 Human P08721 Rat p10451 Human P10451-2 Human
Product By Gene ID	6696
Alternate Names	BNSP Bone sialoprotein 1 MGC110940 Nephropontin osteopontin secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1) secreted phosphoprotein-1 (osteopontin, bone sialoprotein) SPP-1 SPP1/CALPHA1 fusion Urinary stone protein uropontin Uropontin

Research Areas for Osteopontin/OPN

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Biologically Active Proteins
Cancer
Cellular Markers
Extracellular Matrix
Hypoxia

Related Osteopontin/OPN Blog Posts

Check out the latest blog posts on Osteopontin/OPN.

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents Jamshed Arslan, Pharm D, PhD The dorsal root ganglia (DRG) are a collection of cell bodies of sensory nerves carrying sensory information – including nociception, mechanoreception and proprioception – from periphera...    Read more.

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