ORP1 Antibody - BSA Free

Immunohistochemistry-Paraffin: ORP1 Antibody [NBP1-92234] - Staining of human gall bladder shows moderate cytoplasmic, membranous and nuclear positivity in glandular cells.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

ORP1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit ORP1 Antibody - BSA Free (NBP1-92234) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: FTGRKELVMLLLEYNADTTIVNGSGQTAKEVTHAEEIRSMLEAVERTQQRKLEELLLAAAREGKTTELTALLNRPNPPDVNCSDQLGN
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OSBPL1A
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  ORP1 Protein (NBP1-92234PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%) Rat (86%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ORP1 Antibody - BSA Free

• FLJ10217
• ORP-1oxysterol-binding protein-related protein 1 variant 1
• ORP1oxysterol-binding protein-related protein 1
• OSBP8
• OSBPL1
• OSBPL1B
• OSBP-related protein 1
• oxysterol binding protein-like 1A
• oxysterol binding protein-like 1B
• oxysterol-binding protein-related protein 1 variant 2

Background

Oxysterols are oxygenated derivatives of cholesterol that have a number of biological effects and play a key role in the maintenance of the body cholesterol balance. ORP1 is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that are believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OSBPL1A