ORP1 Antibody (23GB4065)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow, ICC/IF, Mycoplasma
• Clone: 23GB4065
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

ORP1 Antibody (23GB4065) Summary

• Immunogen: A synthesized peptide derived from human ORP1 (Uniprot: Q9BXW6)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: OSBPL1A
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for ORP1 Antibody (23GB4065)

• FLJ10217
• ORP-1oxysterol-binding protein-related protein 1 variant 1
• ORP1oxysterol-binding protein-related protein 1
• OSBP8
• OSBPL1
• OSBPL1B
• OSBP-related protein 1
• oxysterol binding protein-like 1A
• oxysterol binding protein-like 1B
• oxysterol-binding protein-related protein 1 variant 2

Background

Oxysterols are oxygenated derivatives of cholesterol that have a number of biological effects and play a key role in the maintenance of the body cholesterol balance. ORP1 is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that are believed to transport sterols from lysosomes to the nucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OSBPL1A