Ornithine Decarboxylase Antibody (MP16-2)

Product Discontinued

Ornithine Decarboxylase Antibody (MP16-2) Summary

• Immunogen: A synthetic hexadecapeptide (KPDEKYYSSSIWGPTC) (aa345-360) from rat ODC
• Localization: Cytoplasmic
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ODC1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Frozen 1:10 - 1:500
• Control:

  Ornithine Decarboxylase Overexpression Lysate

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4) and 0.2% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein G purified

Alternate Names for Ornithine Decarboxylase Antibody (MP16-2)

• ODC
• ODC1
• ODCEC 4.1.1.17
• ornithine decarboxylase 1
• ornithine decarboxylase

Background

Ornithine Decarboxylase (ODC) is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ODC1
• Entrez:
  • 4953(Human)
  • 18263(Mouse)
  • 24609(Rat)
• Uniprot:
  • O14977(Human)