ORC4L Antibody

Western Blot: ORC4L Antibody [NBP2-19633] - Sample (30 ug of whole cell lysate) A: A549 10% SDS PAGE gel, diluted at 1:1000.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

ORC4L Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the center region of human ORC4L. The exact sequence is proprietary.
• Localization: Nucleus
• Predicted Species: Mouse (91%), Rat (90%), Bovine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ORC4
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for ORC4L Antibody

• HsORC4
• ORC4LFLJ46668
• ORC4P
• origin recognition complex subunit 4
• origin recognition complex, subunit 4 (yeast homolog)-like
• origin recognition complex, subunit 4 homolog (S. cerevisiae)
• origin recognition complex, subunit 4 homolog
• origin recognition complex, subunit 4
• origin recognition complex, subunit 4-like (S. cerevisiae)
• origin recognition complex, subunit 4-like (yeast)
• origin recognition complex, subunit 4-like

Background

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown to form a core complex with ORC2L, -3L, and -5L. Three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: ORC4
• Uniprot:
  • O43929(Human)