Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, Ca
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown to form a core complex with ORC2L, -3L, and -5L. Three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq]. Transcript Variant: This variant (2) represents the longest transcript. It differs in the 5' UTR, and encodes the same protein, as compared to variants 1 and 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Bioinformatics
| Product By Gene ID |
5000 |
| Alternate Names |
- HsORC4
- ORC4LFLJ46668
- ORC4P
- origin recognition complex subunit 4
- origin recognition complex, subunit 4 (yeast homolog)-like
- origin recognition complex, subunit 4 homolog (S. cerevisiae)
- origin recognition complex, subunit 4 homolog
- origin recognition complex, subunit 4
- origin recognition complex, subunit 4-like (S. cerevisiae)
- origin recognition complex, subunit 4-like (yeast)
- origin recognition complex, subunit 4-like
|