Orc2 Antibody (C.15200198)

Western Blot: Orc2 Antibody (C.15200198) [NBP2-59237] - RIPA cell lysates from HeLa cells (30 ug) were analyzed using the antibody against ORC2 diluted 1:500 in PBS-Tween containing 10% milk. The position of the protein of interest is indicated on the right (expected size: 66 kDa); the marker (kDa) is shown on the left.

Product Discontinued

Orc2 Antibody (C.15200198) Summary

• Immunogen: The exact immunogen is propietary information.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ORC2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide and 0.05% ProClin 300
• Purity: Protein G purified

Alternate Names for Orc2 Antibody (C.15200198)

• ORC2Lorigin recognition complex subunit 2
• origin recognition complex protein 2 homolog
• origin recognition complex, subunit 2 (yeast homolog)-like
• origin recognition complex, subunit 2 homolog (yeast)
• origin recognition complex, subunit 2 homolog
• origin recognition complex, subunit 2
• origin recognition complex, subunit 2-like (yeast)
• origin recognition complex, subunit 2-like

Background

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ORC2