OBFC1 Antibody (OTI2E4) [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: WB, Flow, ICC/IF, CyTOF-ready
• Clone: OTI2E4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 525

OBFC1 Antibody (OTI2E4) [Janelia Fluor® 525] Summary

• Immunogen: Full length human recombinant protein of human OBFC1 (NP_079204) produced in HEK293T cell.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: STN1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for OBFC1 Antibody (OTI2E4) [Janelia Fluor® 525]

• AAF44
• AAF-44
• alpha accessory factor 44
• bA541N10.2
• CST complex subunit STN1
• oligonucleotide/oligosaccharide-binding fold containing 1
• Oligonucleotide/oligosaccharide-binding fold-containing protein 1
• replication protein A 32 kDa subunit
• RP11-541N10.2
• RPA-32
• STN1FLJ22559
• Suppressor of cdc thirteen homolog

Background

OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNApolymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 (PubMed19119139)). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM613130) (Miyake et al., 2009 (PubMed 19854130)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: STN1