OBFC1 Products

Description

OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNApolymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 (PubMed19119139)). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM613130) (Miyake et al., 2009 (PubMed 19854130)).(supplied by OMIM)

Bioinformatics

Uniprot	NM_024928 Human AAH17400 Human
Product By Gene ID	79991
Alternate Names	replication protein A 32 kDa subunit AAF44 CST complex subunit STN1 Suppressor of cdc thirteen homolog alpha accessory factor 44 Oligonucleotide/oligosaccharide-binding fold-containing protein 1 RPA-32 bA541N10.2 RP11-541N10.2 STN1FLJ22559 AAF-44 oligonucleotide/oligosaccharide-binding fold containing 1

Diseases related to OBFC1

Discover more about diseases related to OBFC1.

Cardiovascular Diseases
Cholangiocarcinoma
Malignant Neoplasm Of Prostate
Anemia
Pulmonary Fibrosis
Telomere Shortening
Fibrosis
Malignant Neoplasms
Aplastic Anemia
Malignant Neoplasm Of Ovary
Dyskeratosis Congenita
Dysequilibrium Syndrome
Dyskeratosis

Pathways for OBFC1

View related products by pathway and learn more about each of the pathways below.

Telomere Maintenance
Senescence
Replicative Senescence
Aging

Bioinformatics Tool for OBFC1

Discover related pathways, diseases and genes to OBFC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.