NUP214 Antibody

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Independent Antibodies: Western Blot: NUP214 Antibody [NB100-2245] - Detection of Human and Mouse NUP214 on HeLa whole cell lysate using NB100-2245. NUP214 was also immunoprecipitated using rabbit anti-NUP214 ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml

Order Details

NUP214 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 2050 and the C-terminus (residue 2090) of human Nuceloporin 214 using the numbering given in entry NP_005076.3 (GeneID 8021).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NUP214
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Publications
Read Publication using NB100-2245.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for NUP214 Antibody

  • 214 kDa nucleoporin
  • CAINputative oncogene
  • D9S46Enuclear pore complex protein Nup214
  • KIAA0023
  • MGC104525
  • N214
  • nucleoporin 214kD (CAIN)
  • nucleoporin 214kDa
  • Nucleoporin Nup214
  • p250
  • Protein CAN

Background

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for NUP214 Antibody (NB100-2245)(1)


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Bioinformatics

Gene Symbol NUP214
Entrez
Uniprot