Nucleoporin 107 Antibody - BSA Free

Western Blot: Nucleoporin 107 Antibody [NBP1-76926] - A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL.

Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody - BSA Free [NBP1-76926] - Immunofluorescence of Nucleoporin 107 in A549 cells with Nucleoporin 107 antibody at 10 ug/mL.

Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody - BSA Free [NBP1-76926] - Immunocytochemistry of Nucleoporin 107 in A549 cells with Nucleoporin 107 antibody at 10 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Nucleoporin 107 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Nucleoporin 107 Antibody - BSA Free (NBP1-76926) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. Anti-Nucleoporin 107 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Antibody was raised against a 20 amino acid synthetic peptide from near the center of human NUP107. The immunogen is located within amino acids 370 - 420 of NUP107. Amino Acid Squence: HDPNVNGGTELEPVEGNPYR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NUP107
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 10 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  Nucleoporin 107 Peptide (NBP1-76926PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for Nucleoporin 107 Antibody - BSA Free

• nuclear pore complex protein Nup107
• nucleoporin 107kDa
• NUP84Nucleoporin Nup107,107 kDa nucleoporin

Background

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Nucleoporin 107 Antibody (NBP1-76926)(1)

Publication using NBP1-76926

• Bilir S, Kojidani T, Mori C et al. Roles of Nup133, Nup153 and membrane fenestrations in assembly of the nuclear pore complex at the end of mitosis Genes Cells 2019-02-28 [PMID: 30821042] (ICC/IF, Human)

Bioinformatics

• Gene Symbol: NUP107
• Uniprot:
  • P57740(Human)