Nucleoporin 107 Antibody

Images

 
Western Blot: Nucleoporin 107 Antibody [NBP1-76926] - A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody [NBP1-76926] - Immunofluorescence of NUP107 in A549 cells with NUP107 antibody at 10 ug/mL.
Immunocytochemistry/ Immunofluorescence: Nucleoporin 107 Antibody [NBP1-76926] - A549 cells with Nucleoporin 107 antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Nucleoporin 107 Antibody Summary

Immunogen
Antibody was raised against a 20 amino acid synthetic peptide from near the center of human NUP107. The immunogen is located within amino acids 370 - 420 of NUP107.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NUP107
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000
Control Peptide
Publications
Read Publication using
NBP1-76926 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for Nucleoporin 107 Antibody

  • nuclear pore complex protein Nup107
  • nucleoporin 107kDa
  • NUP84Nucleoporin Nup107,107 kDa nucleoporin

Background

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Nucleoporin 107 Antibody (NBP1-76926)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.


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ICC/IF
(1)
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Filter By Species
Human
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol NUP107
Uniprot