NPRL3 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: NPRL3 Antibody [NBP1-88447] - Staining of human cell line A-431 shows localization to cytosol. Antibody staining is shown in green.

Immunohistochemistry-Paraffin: NPRL3 Antibody [NBP1-88447] - Staining of human endometrium shows positivity in glandular cells.

Immunohistochemistry-Paraffin: NPRL3 Antibody [NBP1-88447] - Staining of human prostate shows positivity in glandular cells.

Product Discontinued

NPRL3 Antibody - BSA Free Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: GDSRFSDVILATILATKSEMCGQKFELKIDNVRFVGHPTLLQHALGQISKTDPSPKREAPTMILFNVVFALRANADPSVINCLHNLSRRIATVLQHEERRCQYLTREAKLILALQDEVSAMADGNEGPQSPFHHILPKCK
• Predicted Species: Mouse (98%), Rat (97%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NPRL3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
  • Western Blot Reported in scientific literature (PMID:35831510)
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for NPRL3 Antibody - BSA Free

• -14 gene protein
• Alpha-globin regulatory element-containing gene protein
• C16orf35
• CGTHBAchromosome 16 open reading frame 35
• conserved gene telomeric to alpha globin cluster
• MAREHS-40
• nitrogen permease regulator 3-like protein
• nitrogen permease regulator-like 3 (S. cerevisiae)
• NPR3
• Protein CGTHBA
• RMD11

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NPRL3 Antibody (NBP1-88447)(4)

Publications using NBP1-88447

• Yang S, Ting CY, Lilly MA., et Al. The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs Mol Cell 2024-02-07 [PMID: 38325378]
• Valenstein ML, Rogala KB, Lalgudi PV et al. Structure of the nutrient-sensing hub GATOR2 Nature 2022-07-01 [PMID: 35831510] (WB, Human)
• Fang Y, Jiang Q, Li S et al. Opposing functions of ?-arrestin 1 and 2 in Parkinson's disease via microglia inflammation and Nprl3 Cell Death & Differentiation 2021-06-01 [PMID: 33686256]
• Peng M, Yin N, Li MO. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017-02-15 [PMID: 28199315]

Bioinformatics

• Gene Symbol: NPRL3