Norrin/NDP Antibody


Western Blot: Norrin/NDP Antibody [NBP1-77014] - Jurkat cell lysate with Norrin antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry/ Immunofluorescence: Norrin/NDP Antibody [NBP1-77014] - Jurkat cells with NDP/Norrin antibody at 5 ug/ml.

Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
1 mg/ml

Order Details

Norrin/NDP Antibody Summary

Antibody was raised against an 18 amino acid peptide from near the amino terminus of human Norrin
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified


Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
15 kDa
Control Peptide
NDP/Norrin Peptide (NBP1-77014PEP)

Alternate Names for Norrin/NDP Antibody

  • EVR2
  • exudative vitreoretinopathy 2 (X-linked)
  • FEVR
  • ND
  • NDP
  • Norrie disease (pseudoglioma)
  • Norrie disease protein
  • norrin
  • X-linked exudative vitreoretinopathy 2 protein


Norrie disease is an X-linked genetic disorder characterized by progressive atrophy of the eyes, mental disturbances and deafness. The gene responsible for this disease was initially identified through positional cloning. Norrin, the gene product, encodes a small secreted, cysteine-rich protein that is thought to act as a ligand for the Wnt-receptor/beta-catenin signal pathway despite having sequence homology with the Wnt family of proteins. Mice lacking this gene have abnormal blood vessel growth in the vitreous and a disorganized retina; transgenic ectopic expression of Norrin restores normal retinal vasculature. Recent evidence shows that Norrin can attenuate tPA and uPA-mediated death of transformed rat retinal ganglion cells (RGC-5) by activating the Wnt/beta-catenin pathway and regulating the phosphorylation of LRP-1, a cell surface receptor for tPA and uPA, suggesting the Norrin may function in vivo by regulating kinases which may alter the phosphorylation of LRP-1.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, S-ELISA
Species: Hu, Mu
Applications: WB, Flow, ICC
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Species: Hu, Mu
Applications: WB, IHC, IHC-Fr, IHC-P, PEP-ELISA
Species: Hu
Applications: WB
Species: Hu, Mu
Applications: WB, IHC, IHC-Fr
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Rt, Ca
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Species: Hu
Applications: WB, Flow
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-Fr, PEP-ELISA, IHC-WhMt
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
Species: Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Species: Hu, Rt
Applications: ELISA, IP, S-ELISA
Species: Hu
Applications: WB, ELISA, PA

Publications for Norrin/NDP Antibody (NBP1-77014) (0)

There are no publications for Norrin/NDP Antibody (NBP1-77014).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Norrin/NDP Antibody (NBP1-77014) (0)

There are no reviews for Norrin/NDP Antibody (NBP1-77014). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Norrin/NDP Antibody (NBP1-77014) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Additional Norrin/NDP Antibody Products

Related Products by Gene

Bioinformatics Tool for Norrin/NDP Antibody (NBP1-77014)

Discover related pathways, diseases and genes to Norrin/NDP Antibody (NBP1-77014). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Norrin/NDP Antibody (NBP1-77014)

Discover more about diseases related to Norrin/NDP Antibody (NBP1-77014).

Pathways for Norrin/NDP Antibody (NBP1-77014)

View related products by pathway.

PTMs for Norrin/NDP Antibody (NBP1-77014)

Learn more about PTMs related to Norrin/NDP Antibody (NBP1-77014).

Research Areas for Norrin/NDP Antibody (NBP1-77014)

Find related products by research area.

Blogs on Norrin/NDP

There are no specific blogs for Norrin/NDP, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol NDP

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NBP1-77014 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought