NMDAR3B Antibody - BSA Free

Western Blot: NMDAR3B Antibody [NBP2-94574] - Analysis of extracts of rat brain, using NMDAR3B at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

Product Discontinued

NMDAR3B Antibody - BSA Free Summary

• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-410 of human GRIN3B (NP_619635.1). RTQDPGGLVALWTSRAGRPPQLVLDLSRRDTGDAGLRARLAPMAAPVGGEAPVPAAVLLGCDIARARRVLEAVPPGPHWLLGTPLPPKALPTAGLPPGLLALGEVARPPLEAAIHDIVQLVARALGSAAQVQPKRALLPAPVNCGDLQPAGPESPGRFLARFLANTSFQGRTGPVWVTGSSQVHMSRHFKVWSLRRDPRGAPAWATVGSWRDGQLDLEPGGASARPPPPQG
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GRIN3B
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500-1:1000
• Theoretical MW: 112 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for NMDAR3B Antibody - BSA Free

• GluN3B
• glutamate [NMDA] receptor subunit 3B
• glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
• GRIN3B
• NMDA receptor subunit 3B
• NMDA type glutamate receptor subunit NR3B
• NMDAR3B
• N-methyl-D-aspartate receptor subtype 3B
• NR3B

Background

The GRIN3B (NMDAR3B) gene encodes a 1,043 amino acid long, nearly 113 kDA glutamate receptor iontrophic, NMDA 3B that is a glycine controlled receptor that functions in glutamate-gated ion channels with reduced single-channel conductance, calcium, and voltage-sensitivity to magnesium. GRIN3B functions in glutamic acid signaling, the pathogenesis of ALS, the neuroactive ligand-receptor interaction, and the dopamine DARPP32 feedback onto cAMP pathway. This gene has been linked to HIV type 1, neuroblastoma, pain syndrome, opiod abuse, immunodeficiency, and alzheimer's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GRIN3B