The GRIN3B (NMDAR3B) gene encodes a 1,043 amino acid long, nearly 113 kDA glutamate receptor iontrophic, NMDA 3B that is a glycine controlled receptor that functions in glutamate-gated ion channels with reduced single-channel conductance, calcium, and voltage-sensitivity to magnesium. GRIN3B functions in glutamic acid signaling, the pathogenesis of ALS, the neuroactive ligand-receptor interaction, and the dopamine DARPP32 feedback onto cAMP pathway. This gene has been linked to HIV type 1, neuroblastoma, pain syndrome, opiod abuse, immunodeficiency, and alzheimer's disease.
|Product By Gene ID
- NMDA type glutamate receptor subunit NR3B
- N-methyl-D-aspartate receptor subtype 3B
- NMDA receptor subunit 3B
- glutamate [NMDA] receptor subunit 3B
- glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
Bioinformatics Tool for NMDAR3B
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