NMDAR3B Products

Description

The GRIN3B (NMDAR3B) gene encodes a 1,043 amino acid long, nearly 113 kDA glutamate receptor iontrophic, NMDA 3B that is a glycine controlled receptor that functions in glutamate-gated ion channels with reduced single-channel conductance, calcium, and voltage-sensitivity to magnesium. GRIN3B functions in glutamic acid signaling, the pathogenesis of ALS, the neuroactive ligand-receptor interaction, and the dopamine DARPP32 feedback onto cAMP pathway. This gene has been linked to HIV type 1, neuroblastoma, pain syndrome, opiod abuse, immunodeficiency, and alzheimer's disease.

Bioinformatics

Uniprot	NP_619635.1 Human
Product By Gene ID	116444
Alternate Names	glutamate [NMDA] receptor subunit 3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B NMDA receptor subunit 3B NMDA type glutamate receptor subunit NR3B NMDAR3B N-methyl-D-aspartate receptor subtype 3B NR3B