NKX3.1 Antibody (738907) [Janelia Fluor® 669]

• Reactivity: Mu
• Applications: ICC/IF
• Clone: 738907
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Janelia Fluor 669

NKX3.1 Antibody (738907) [Janelia Fluor® 669] Summary

• Immunogen: E. coli-derived recombinant mouse NKX3.1
  Met1-Pro124 (predicted)
  Accession # P97436
• Specificity: Detects mouse NKX3.1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) NKX3.1 or rhNKX6.1 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: NKX3-1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for NKX3.1 Antibody (738907) [Janelia Fluor® 669]

• BAPX2
• BAPX2homeobox protein Nkx-3.1
• Homeobox protein NK-3 homolog A
• NK homeobox (Drosophila), family 3, A
• NK3 homeobox 1
• NK3 transcription factor homolog A
• NK3 transcription factor related, locus 1 (Drosophila)
• NK3 transcription factor related, locus 1
• NKX3.1
• NKX3.1NKX3
• NKX3-1
• NKX3A
• NKX3ANK homeobox, family 3, A

Background

Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in prostate cancer. But neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NKX3-1