NKp80/KLRF1 Antibody (5D12) [Janelia Fluor® 646]

• Reactivity: Hu, Pm, Mu(-), Rt(-)
• Applications: Flow, IP
• Clone: 5D12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

NKp80/KLRF1 Antibody (5D12) [Janelia Fluor® 646] Summary

• Immunogen: Recombinant human NKp80/KLRF1 extracellular domain
• Epitope: The mouse monoclonal antibody 5D12 recognizes an extracellular epitope of human NKp80/KLRF1.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: KLRF1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for NKp80/KLRF1 Antibody (5D12) [Janelia Fluor® 646]

• Activating coreceptor NKp80
• CLEC5C
• CLEC5CMGC119908
• C-type lectin domain family 5 member C
• killer cell lectin-like receptor F1
• killer cell lectin-like receptor subfamily F member 1
• killer cell lectin-like receptor subfamily F, member 1
• KLRF1
• Lectin-like receptor F1
• MGC119907
• MGC119909
• ML
• NKp80

Background

KLRF1 is a gene that codes for a protein that is helps to facilitate the natural killer-mefiated cytolysis of PHA-induced lymphoblasts and is strongly expressed in the peripheral blood leukocytes and the spleen, with a weaker expression in the lymph nodes and the adult liver. There are four isoforms of KLRF1, with lengths of 232, 182, 64, and 78 amino acids and weights of approximately 27, 21, 7, and 9 kDa respectively. There have been studies conducted on diseases and disorders relating to this gene, including hepatitis b and hepatitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KLRF1