Recombinant Human NKp44/NCR2 Protein

Product Discontinued

Recombinant Human NKp44/NCR2 Protein Summary

• Description: A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 19-130 of Human NKp44/NCR2
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSQAQSKAQV LQSVAGQTLT VRCQYPPTGS LYEKKGWCKE ASALVCIRLV TSSKPRTMAW TSRFTIWDDP DAGFFTVTMT DLREEDSGHY WCRIYRPSDN SVSKSVRFYL VVS

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: NCR2
• Purity: >80%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Application Notes: Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
• Theoretical MW: 15 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol, 0.4M UREA
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >80%, by SDS-PAGE

Alternate Names for Recombinant Human NKp44/NCR2 Protein

• CD336 antigen
• CD336
• LY95
• LY95lymphocyte antigen 95 homolog (activating NK-receptor; NK-p44)
• lymphocyte antigen 95 (activating NK-receptor; NK-p44)
• Lymphocyte antigen 95 homolog
• natural cytotoxicity triggering receptor 2
• Natural killer cell p44-related protein
• NCR2
• NK cell activating receptor (NKp44)
• NK cell-activating receptor
• NKp44
• NK-p44dJ149M18.1

Background

NKp44 (NCR2) is a member of the natural cytotoxicity receptor (NCR) family that is expressed on activated human NK cells. NKp44 displays a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), likely involved in the association with KARAP/DAP12 molecules. Gene coding for NKp44 maps on human chromosome 6p21.1.This antibody is specific for NKp44 and does not cross react with NKp30 and NKp46.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: NCR2