Recombinant Human NKIRAS2 His Protein

SDS-Page: Recombinant Human NKIRAS2 Protein [NBP1-99008] - 15% SDS-PAGE (3ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human NKIRAS2 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-191 of Human NKIRAS2
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMGKSCK VVVCGQASVG KTSILEQLLY GNHVVGSEMI ETQEDIYVGS IETDRGVREQ VRFYDTRGLR DGAELPRHCF SCTDGYVLVY STDSRESFQR VELLKKEIDK SKDKKEVTIV VLGNKCDLQE QRRVDPDVAQ HWAKSEKVKL WEVSVADRRS LLEPFVYLAS KMTQPQSKSA FPLSRKNKGS GSLDG

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: NKIRAS2
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 24 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 1 mM DTT, 10% glycerol, 0.1 M NaCl
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human NKIRAS2 His Protein

• DKFZP434N1526
• I-kappa-B-interacting Ras-like protein 2
• Kappa B-Ras protein 2
• kappaB-Ras2
• KBRAS2DKFZp434N1526
• MGC74742
• NF-kappa-B inhibitor-interacting Ras-like protein 2
• NFKB inhibitor interacting Ras-like 2
• NFKB inhibitor interacting Ras-like protein 2

Background

NFKB inhibitor interacting Ras-like 2 (NKIRAS2), also known as KBRAS2, is similar to the Ras-like small GTPases that associate with IkappaB. These Ras-like proteins, NKIRAS1 and NKIRAS2, interact with the PEST domains of IkB alpha and IkB beta and decrease their rate of degradation. NKIRAS2 shows 71% identity to KBRAS1. NKIRAS2 is an inhibitor of the transcription factor NF-kappaB. Recombinant human NKIRAS2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: NKIRAS2