NgR2/NgRH1/RTN4RL2 Antibody (333413) [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clone: 333413
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

NgR2/NgRH1/RTN4RL2 Antibody (333413) [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human NgR2/NgRH1
  Ala28-Leu401
  Accession # Q86UN3
• Specificity: Detects human NgR2/NgRH1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) NgR3 or rhNgR is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: RTN4RL2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NgR2/NgRH1/RTN4RL2 Antibody (333413) [Unconjugated]

• NgR2
• NgRH1
• reticulon 4 receptor-like 2
• RTN4RL2

Background

NgR2, also known as reticulon 4 receptor-like 2 and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- as well as the C-terminus. Membrane-anchored NgR2 can be solubilized through the action of phospholipase or an unidentified MT-MMP to generate a 46 kDa soluble receptor. Mature human NgR2 shares 48% aa sequence identity with human NgR3. It also shares 96% aa sequence identity with mouse and rat mature NgR2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RTN4RL2
• Uniprot:
  • Q86UN3()