NgR3/NgRH2/RTN4RL1 Antibody [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

NgR3/NgRH2/RTN4RL1 Antibody [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human NgR3/NgRH2
  Cys25-Ala419
  Accession # Q86UN2
• Specificity: Detects human NgR3/NgRH2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross‑reactivity with recombinant human (rh) NgRH1 is observed and less than 1% cross-reactivity with rhNgR is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: RTN4RL1
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for NgR3/NgRH2/RTN4RL1 Antibody [Unconjugated]

• DKFZp547J144
• NgR3
• NgRH2
• NGRL2
• nogo receptor-like 2
• Nogo-66 receptor homolog 2
• Nogo-66 receptor-related protein 3
• reticulon 4 receptor-like 1
• reticulon-4 receptor-like 1
• RTN4RL1

Background

NgR3, also known as Nogo 66 receptor homolog 2 (NgRH2) and reticulon 4 receptor-like 1 (RTN4RL1), is a 60 kDa GPI-linked glycoprotein belonging to the family of leucine-rich repeat (LRR) proteins. It contains eight central LRRs that are flanked by a LRR N-terminal subdomain and a cysteine-rich C-terminal subdomain. Human NgR3 shares approximately 89% amino acid sequence homology with the mouse or rat protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NgR3/NgRH2/RTN4RL1 Antibody (AF2920)(1)

Publication using AF2920

• Hofer T, Tangkeangsirisin W, Kennedy MG, Mage RG, Raiker SJ, Venkatesh K, Lee H, Giger RJ, Rader C Chimeric rabbit/human Fab and IgG specific for members of the Nogo-66 receptor family selected for species cross-reactivity with an improved phage display vector. J. Immunol. Methods, 2006-11-07;318(1):75-87. 2006-11-07 [PMID: 17140598] (Western Blot, Human)

Bioinformatics

• Gene Symbol: RTN4RL1
• Uniprot:
  • Q86UN2()